In patients with head and neck cancer, PET with [F 18] fluorodeoxyglucose (FDG) is both more sensitive and specific than CT or MR for detection of both primary and recurrent neoplasm. On PET alone, however, limited spatial resolution and lack of anatomic landmarks hinder accurate tumor localization, particularly in the head and neck. In addition, variable uptake of FDG in normal structures such as the nasal turbinates, pterygoid muscles, extraocular muscles, the parotid and submandibular glands, and lymphoid tissue of the adenoids and upper Waldeyer’s ring may confuse interpretation and result in false positives (1). Although FDG uptake in primary neoplasms is usually greater than that observed in even the most metabolically active of normal structures (1), overlap between tumor and physiologic uptake may confound interpretation. A new device, the combined PET/CT tomograph, permits acquisition of co-registered high-resolution anatomic and FDG-PET images in the same session (2). Our purpose was to map metabolic (FDG uptake) data to normal anatomic structures on combined PET/CT images to provide an atlas of physiologic uptake of FDG in the head and neck.