Vol. 2, Article 4 Neurographics logo Lieberman et al.

 

Introduction

A new tumor composed of cells resembling tanycytes has recently been described in the pathology literature (1,2). Tihan et al. in 1999 described a series of patients with neoplasms having a distinctive monomorphous pilomyxoid histological pattern (1). The majority of these neoplasms were located in the hypothalamic-chiasmatic region and were similar histologically to an astrocytoma but behaved more aggressively with a higher rate of recurrence.

Demographics

Patient Age(y)/Sex Symptoms Location Surgery Therapy Follow-Up
2 2/F Headache
Nausea
Emesis
Hypothalamus / suprasellar Partial resection Radiation: 5012 cGy
Chemotherapy: Carboplatin Vincrinstine
Deceased
2 2/M Diplopia
Decrease in left eye vision
Hypothalamus / suprasellar Partial resection Radiation: 5040 cGy
Chemotherapy: Carboplatin Vincristine
Decrease residual tumor
3 3/M Headache
Emesis
Hypothalamus / suprasellar Partial resection Radiation: 5400 cGy
Chemotherapy: Carboplatin Vincrinstine
Deceased
4 26/F Galactorrhea Hypothalamus Complete resection Radiation: 5400 cGy Lost to follow up
5 56/F Headache Left lateral ventricle Complete resection None No recurrence at 4 mos

 



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